Neo-Calvinism critically advances Reformed orthodoxy for the sake of modern life. Birthed in the Netherlands at the turn to the twentieth century, initiated by Abraham Kuyper (1837-1920) and Herman Bavinck (1854-1921), it argued that a life before God entailed the leavening of faith over all human existence. While the movement originated in the Netherlands, the tradition now has a global reach, with practitioners and thinkers applying its insights in diverse ways and in their own contexts. This handbook is a genealogical introduction to this lively and modern branch of the Reformed tradition, with contributors that reflect its global reach. Its four sections chart the theological roots, important original figures, historical contours and the contemporary influence of neo-Calvinism across a diversity of fields.