The journey to 100 friends begins with a single conversation. Socially anxious high school student Shoko Komi's greatest dream is to make some friends, but everyone at school mistakes her crippling social anxiety for cool reserve. Luckily she meets Tadano, a timid wallflower who decides to step out of his comfort zone in order to help her achieve her goal of making 100 friends. Komi's final year of high school is going great! She led her class to victory at the culture festival (i.e., their ramen was a hit and nothing burned down), and she's getting close to her goal of 100 friends! But her younger brother Shosuke isn't having the same luck. Recently a menacing new group led by Tadano's sister has started to target him, and they're determined to make him smile!