This book explores the transformative role of Artificial Intelligence (AI) in enhancing Customer Relationship Management (CRM) systems, specifically within Small and Medium-sized Enterprises (SMEs). It examines how AI-integrated CRM tools optimize customer engagement, streamline marketing strategies, personalize experiences, and improve decision-making processes. Through real-world case studies and recent research, the book highlights practical applications, challenges, and the measurable impact of AI on sales growth and customer loyalty. It offers valuable insights for business owners, CRM professionals, and researchers aiming to understand the intersection of AI and customer-centric business practices in the SME context.