This book offers a theoretical and practical guide to transform university teaching through active methodologies. Based on contemporary pedagogical foundations, it analyzes approaches such as project-based learning, problem-based learning, flipped classroom, gamification, service-learning, design thinking and dialogic learning. It includes proposals for didactic planning, formative evaluation, integration of technologies, practical examples and real experiences of educational innovation in Latin America. Aimed at teachers, trainers and pedagogy students, it seeks to rethink the role of teachers and students in diverse, inclusive scenarios committed to social change.