The Arachnid family, comprising Professor Arachnid, his wife Madame Web, and their many spider offspring, relocates to Sinktop Apartments. Their arrival is met with immediate hostility from the Cockroach family, Bartholomew and Beatrice, and their children Pip, Squeak, and Dot, who inhabit the apartment above. This initial clash, stemming from a rude encounter, escalates into a humorous and increasingly absurd feud. The story details their comical disputes, often driven by misunderstandings and differing interpretations of neighborly conduct, with the Cockroaches' elevated position in Upper Cabinet Apartments contributing to their condescending attitude towards the Arachnids below.