The Glioblastoma Compass is a comprehensive, compassionate, and deeply informative guide designed to empower patients, families, and healthcare professionals navigating one of the most challenging diagnoses in neuro-oncology. With glioblastoma known for its aggressive nature and complex treatment pathways, this book serves as a steady, practical compass-bringing clarity, direction, and hope to a journey that often feels overwhelming. Grounded in the most up-to-date research and clinical practice, The Glioblastoma Compass breaks down essential knowledge in a clear, accessible manner. Readers are guided through the fundamentals of glioblastoma biology, how and why it develops, modern diagnostic techniques, and what to expect from imaging and pathology reports. The book unpacks every major component of evidence-based management, including surgical approaches, radiotherapy options, chemotherapy regimens like temozolomide, tumor-treating fields, corticosteroid management, and cutting-edge targeted and immunotherapies currently shaping the future of care. Beyond medical treatment, this book recognizes the humanity of the journey. It offers practical strategies for managing symptoms such as seizures, cognitive changes, fatigue, and headaches, as well as guidance on rehabilitation, nutrition, psychological support, and maintaining quality of life. Families will find valuable chapters on caregiving, communication with the medical team, navigating clinical trials, and planning ahead with dignity and autonomy. Written with empathy and precision, The Glioblastoma Compass also explores the rapidly evolving landscape of research-from genetic profiling and precision medicine to experimental vaccines, CAR-T therapies, and emerging biomarkers. Each section sheds light on both current standards and the promising innovations that offer new avenues of hope. Whether you are newly diagnosed, supporting a loved one, or providing care as a health professional, The Glioblastoma Compass equips you with the knowledge, confidence, and direction needed to make informed decisions. It is not just a medical guide-it is a source of strength, understanding, and guidance for one of life's hardest roads.