Cannabis exists in many varieties and sub-species. Among people using cannabis for pain management, OG Shark, Afghani, and Skywalker are among the most popular strains. Each cannabis strain has a different concentration of the cannabinoids tetrahydrocannabinol (THC), cannabidiol (CBD), as well as other compounds. Cultivators and farmers have long been breeding different varieties with certain characteristics to create hybrids and specific strains. Producers grow the plants to have a certain look, taste, and effect on the user and brand them accordingly. Currently, reports on the effects of different cannabis strains come predominantly from people's experiences. Although researchers are studying the effects of a variety of cannabis strains on a range of medical conditions, there is still a long way to go in this area. Read to learn more about cannabis strains, and which are the most popular. Since cannabis is more readily available today than ever before, people need clear, accurate information on the effects of different cannabis strains for medical and recreational purposes. Knowing the composition and physiological and mental effects of cannabis plants can help people and clinicians choose the most appropriate product. Cannabis farmers crossbreed cannabis plants to create new strains that have different levels of THC, CBD, and many other physiologically active compounds. Each plant may have different medicinal and recreational purposes. Researchers need to carry out further studies to better understand this complex plant and its effects on humans.